| ORIGINAL ARTICLE |
|
| Year : 2021 | Volume
: 1
| Issue : 2 | Page : 51-58 |
|
|
Metabolic syndrome among Nigerians with type 2 diabetes mellitus: A comparative study of the diagnostic criteria
Taoreed A Azeez, Jokotade Adeleye, Enigbokan A Omololu, Bolaji Adejimi, John S Oladapo
Endocrinology Unit, Department of Medicine, University College Hospital, Ibadan, Nigeria
Correspondence Address:
Taoreed A Azeez
Endocrinology Unit, Department of Medicine, University College Hospital, Ibadan.
Nigeria
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/JCDM.JCDM_15_21
|
|
|
Background: Metabolic syndrome is associated with increased cardiovascular death. The objectives of this study were to find the frequency of metabolic syndrome among Nigerians with type 2 diabetes and to compare the modified National Cholesterol Education Program on the detection, evaluation, and treatment of high blood cholesterol in adults—Adults Treatment Panel III (NCEP ATP III) criteria and the International Diabetes Federation (IDF) criteria. Materials and Methods: The study involved 134 participants. Sixty-seven were cases with type 2 diabetes, whereas the rest were the controls without type 2 diabetes. Ethical approval was granted by the Institutional Ethics Review Committee. Anthropometric, clinical, and laboratory parameters were obtained using standard protocols. Data were analyzed with SPSS version 22. Means were compared with Student’s t-test, whereas proportions were compared with Pearson’s χ2 test. Point biserial correlation was used to determine the association between the dichotomous variables and interval variables. Agreement between the criteria was tested with Cohen’s kappa test. Results: Type 2 diabetes was associated with a higher prevalence of hypertension and truncal obesity. The frequency of metabolic syndrome was lower with the IDF criteria compared with the modified NCEP criteria (65.7% vs. 71.6%). Although there was a strong agreement between the IDF and the modified NCEP criteria (κ=0.862; P<0.0001), the IDF criteria missed 8.3% of diabetic individuals diagnosed with metabolic syndrome by the modified NCEP criteria. Cardiovascular risk is better predicted when the modified NCEP criteria were used to diagnose metabolic syndrome. Conclusion: Metabolic syndrome is very common among Nigerians with type 2 diabetes, and it is better diagnosed with the modified NCEP ATP III criteria. |
|
|
|
| [FULL TEXT] [PDF]* |
|
 |
|
